Olga Pol Selected Research

cobaltiprotoporphyrin

1/2022	The Beneficial Effects of Heme Oxygenase 1 and Hydrogen Sulfide Activation in the Management of Neuropathic Pain, Anxiety- and Depressive-like Effects of Paclitaxel in Mice.
1/2022	Effects of heme oxygenase 1 in the molecular changes and neuropathy associated with type 2 diabetes in mice.
1/2019	The Effects of Cobalt Protoporphyrin IX and Tricarbonyldichlororuthenium (II) Dimer Treatments and Its Interaction with Nitric Oxide in the Locus Coeruleus of Mice with Peripheral Inflammation.
1/2018	Mechanism implicated in the anti-allodynic and anti-hyperalgesic effects induced by the activation of heme oxygenase 1/carbon monoxide signaling pathway in the central nervous system of mice with neuropathic pain.
10/2017	The Inhibitory Effects of Cobalt Protoporphyrin IX and Cannabinoid 2 Receptor Agonists in Type 2 Diabetic Mice.
2/2016	The antinociceptive effects of a δ-opioid receptor agonist in mice with painful diabetic neuropathy: Involvement of heme oxygenase 1.
1/2016	The Induction of Heme Oxygenase 1 Decreases Painful Diabetic Neuropathy and Enhances the Antinociceptive Effects of Morphine in Diabetic Mice.
10/2014	Treatment with a heme oxygenase 1 inducer enhances the antinociceptive effects of µ-opioid, δ-opioid, and cannabinoid 2 receptors during inflammatory pain.
8/2014	The role of gaseous neurotransmitters in the antinociceptive effects of morphine during acute thermal pain.
8/2013	Effects of treatment with a carbon monoxide-releasing molecule and a heme oxygenase 1 inducer in the antinociceptive effects of morphine in different models of acute and chronic pain in mice.

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Olga Pol Research Topics

Disease

23	Neuralgia (Stump Neuralgia) 01/2022 - 01/2006
20	Pain (Aches) 12/2021 - 01/2007
19	Inflammation (Inflammations) 12/2021 - 08/2003
18	Hyperalgesia 01/2022 - 01/2009
10	Chronic Pain 10/2021 - 08/2013
5	Diabetic Neuropathies (Diabetic Neuropathy) 01/2022 - 01/2016
3	Hyperglycemia 01/2022 - 01/2017
3	Type 2 Diabetes Mellitus (MODY) 01/2022 - 01/2017
3	Osteoarthritis 12/2021 - 12/2019
3	Hypersensitivity (Allergy) 01/2016 - 01/2011
2	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2018 - 01/2017
2	Painful Neuropathy 10/2017 - 01/2017
2	Visceral Pain 08/2013 - 01/2003
1	Peripheral Nervous System Diseases (PNS Diseases) 01/2022
1	Mood Disorders (Mood Disorder) 07/2021
1	Dyslipidemias (Dyslipidemia) 01/2018
1	Obesity 10/2017
1	Body Weight (Weight, Body) 01/2017
1	Diabetes Mellitus 01/2016
1	Acute Pain 08/2014

Drug/Important Bio-Agent (IBA)

21	Heme Oxygenase-1IBA 01/2022 - 01/2012
16	Opioid Receptors (Opioid Receptor)IBA 12/2021 - 01/2004
15	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2019 - 07/2005
14	Morphine (MS Contin)FDA LinkGeneric 07/2021 - 07/2005
12	Carbon MonoxideIBA 01/2021 - 01/2012
11	cobaltiprotoporphyrinIBA 01/2022 - 05/2013
11	Opioid Analgesics (Opioids)IBA 01/2021 - 08/2003
10	Freund's AdjuvantIBA 12/2021 - 07/2007
10	Analgesics (Analgesic Drugs)IBA 12/2021 - 01/2007
9	quinone (benzoquinone)IBA 07/2021 - 01/2017
9	D-Penicillamine (2,5)- EnkephalinIBA 01/2017 - 01/2006
8	tricarbonyldichlororuthenium (II) dimerIBA 01/2019 - 08/2013
7	AntioxidantsIBA 12/2021 - 10/2017
7	Antidepressive Agents (Antidepressants)IBA 10/2021 - 01/2019
7	NAD (NADH)IBA 07/2021 - 01/2017
7	EnzymesIBA 07/2021 - 12/2010
7	Mitogen-Activated Protein KinasesIBA 01/2021 - 12/2017
6	Hydrogen Sulfide (Sulfide, Hydrogen)IBA 01/2022 - 12/2019
6	delta Opioid Receptors (delta Opioid Receptor)IBA 12/2021 - 08/2003
6	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 01/2021 - 07/2005
6	Proteins (Proteins, Gene)FDA Link 12/2020 - 08/2003
6	JHW 015IBA 01/2016 - 09/2010
5	Anti-Anxiety Agents (Anxiolytics)IBA 07/2021 - 01/2018
4	Transcription Factors (Transcription Factor)IBA 12/2021 - 01/2017
4	Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA 07/2021 - 01/2019
4	CannabinoidsIBA 01/2021 - 01/2011
4	Oxidoreductases (Dehydrogenase)IBA 12/2019 - 01/2017
4	Heme Oxygenase (Decyclizing) (Heme Oxygenase)IBA 02/2016 - 05/2013
4	EnkephalinsIBA 10/2014 - 01/2006
3	GYY 4137IBA 01/2022 - 07/2021
3	Methylene Chloride (Dichloromethane)IBA 01/2022 - 07/2021
3	phenylisothiocyanateIBA 12/2021 - 12/2019
3	diallyl disulfide (diallyl disulphide)IBA 12/2021 - 07/2021
3	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 07/2021 - 12/2019
3	Pharmaceutical PreparationsIBA 12/2020 - 08/2014
3	Mitogen-Activated Protein Kinase 3IBA 01/2020 - 01/2019
3	sulforaphaneIBA 01/2019 - 12/2017
3	Cyclic GMP-Dependent Protein Kinases (Protein Kinase G)IBA 04/2011 - 09/2010
3	Messenger RNA (mRNA)IBA 07/2007 - 07/2005
3	kappa Opioid Receptors (kappa Opioid Receptor)IBA 01/2006 - 08/2003
2	Potassium Channels (Potassium Channel)IBA 12/2021 - 07/2021
2	tin protoporphyrin IXIBA 12/2020 - 10/2014
2	NADP (NADPH)IBA 12/2020 - 01/2020
2	allyl isothiocyanateIBA 01/2020 - 12/2019
2	Glutathione Transferase (Glutathione S-Transferase)IBA 01/2020 - 12/2019
2	Nitric Oxide Synthase (NO Synthase)IBA 08/2014 - 01/2006
2	KATP ChannelsIBA 04/2011 - 01/2011
2	Adenosine Triphosphate (ATP)IBA 04/2011 - 01/2011
2	Nitric Oxide DonorsIBA 10/2009 - 01/2007
2	NG-Nitroarginine Methyl Ester (L-NAME)IBA 01/2006 - 07/2005
2	mu Opioid Receptors (mu Opioid Receptor)IBA 01/2006 - 07/2005
2	Croton OilIBA 01/2006 - 07/2005
1	Paclitaxel (Taxol)FDA LinkGeneric 01/2022
1	MorpholinosIBA 07/2021
1	OxindolesIBA 07/2021
1	Iodoacetic AcidIBA 12/2019
1	Nuclear Proteins (Protein, Nuclear)IBA 06/2019
1	oltiprazIBA 06/2019
1	2',6'- dimethyltyrosyl- 1,2,3,4- tetrahydroisoquinoline- 3- carboxylic acid (1H- benzimidazol- 2- yl)(carboxymethyl)methylamideIBA 01/2019
1	Phosphatidylinositols (Phosphatidylinositol)IBA 01/2019
1	JNK Mitogen-Activated Protein KinasesIBA 01/2019
1	Lipoproteins (Lipoprotein)IBA 01/2018
1	HDL LipoproteinsIBA 01/2018
1	Streptozocin (Streptozotocin)FDA Link 01/2018
1	4- (alpha- (4- allyl- 2,5- dimethyl- 1- piperazinyl)- 3- methoxybenzyl)- N,N- diethylbenzamideIBA 01/2017
1	Glucose (Dextrose)FDA LinkGeneric 01/2017
1	Neurotransmitter Agents (Neurotransmitter)IBA 08/2014
1	Formaldehyde (Formol)FDA Link 08/2013
1	AcidsIBA 08/2013
1	Protein Isoforms (Isoforms)IBA 08/2013
1	Trifluoroacetic Acid (Trifluoroacetate)IBA 04/2011
1	SaltsIBA 04/2011
1	Lysine (L-Lysine)FDA Link 04/2011
1	nitroguanidineIBA 04/2011
1	GuanosineIBA 04/2011
1	Guanylate Cyclase (Guanylyl Cyclase)IBA 04/2011

Therapy/Procedure

3	Therapeutics 01/2022 - 01/2007
3	Ligation 01/2020 - 12/2010
2	Drug Therapy (Chemotherapy) 01/2022 - 01/2020
1	Intra-Articular Injections 12/2019